Cpd Nr. | CC50 | HSV-1 | HSV-2 | CVB4 | |||
---|---|---|---|---|---|---|---|
EC50 | SI | EC50 | SI | EC50 | SI | ||
1 | 115.9 | Inactive | Inactive | Inactive | Inactive | 272.4 | 0.43 |
2 | 173.1 | 247.5 | 0.70 | 213.8 | 0.81 | 149.2 | 1.16 |
3 | 376.5 | 428.1 | 0.88 | 361.6 | 1.04 | 342.4 | 1.10 |
4 | 824.7 | 706.4 | 1.17 | 649.2 | 1.27 | 478.9 | 1.72 |
5 | 3840 | 896.4 | 4.28 | 740.8 | 5.18 | 612.8 | 6.27 |
6 | 261.4 | 224.5 | 1.16 | 208.9 | 1.25 | 102.9 | 2.54 |
7 | 105.7 | 73.8 | 1.43 | 81.4 | 1.30 | 38.9 | 2.72 |
8 | 218.5 | 147.1 | 1.49 | 159.6 | 1.37 | 93.6 | 2.33 |
9 | 546.9 | 316.5 | 1.73 | 359.2 | 1.52 | 94.8 | 5.77 |
10 | 198.9 | 162.7 | 1.22 | 184.3 | 1.08 | 124.1 | 1.60 |
11 | 542.6 | 403.9 | 1.34 | 467.3 | 1.16 | 216.2 | 2.51 |
12 | 83.7 | 74.12 | 1.13 | 65.9 | 1.27 | 56.4 | 1.48 |
13 | 652.4 | 594.6 | 1.10 | 681.3 | 0.96 | 371.8 | 1.75 |
14 | 221.8 | 197.3 | 1.12 | 176.4 | 1.26 | 116.8 | 1.90 |
15 | 376.2 | 243.2 | 1.55 | 260.8 | 1.44 | 104.6 | 3.60 |
16 | 934.2 | 582.9 | 1.60 | 624.6 | 1.50 | 316.4 | 2.95 |
17 | 132.7 | 81.2 | 1.63 | 104.8 | 1.27 | 50.2 | 2.64 |
18 | 183.4 | 149.8 | 1.22 | 140.5 | 1.31 | 89.5 | 2.05 |
19 | 236.5 | 189.3 | 1.25 | 174.9 | 1.35 | 157.1 | 1.51 |
20 | 465.3 | 369.1 | 1.26 | 402.9 | 1.15 | 287.6 | 1.62 |
21 | 968.7 | 674.8 | 1.44 | 812.6 | 1.19 | 259.4 | 3.73 |
22 | 127.3 | 76.3 | 1.67 | 89.4 | 1.42 | 41.2 | 3.09 |
23 | 205.6 | 183.6 | 1.12 | 165.2 | 1.24 | 149.2 | 1.38 |
24 | 169.1 | 64.7 | 2.61 | 112.3 | 1.51 | 43.9 | 3.85 |
25 | 431.6 | 307.2 | 1.40 | 284.8 | 1.52 | 204.3 | 2.11 |
26 | 681.2 | 498.2 | 1.37 | 514.6 | 1.32 | 395.6 | 1.72 |
27 | 1034.8 | >1000 | Inactive | >1000 | Inactive | 475.3 | 2.17 |
28 | 189.6 | 162.4 | 1.17 | 178.6 | 1.06 | 57.3 | 3.31 |
Acyclovir | 648.2 | 2.3 | 281.83 | 1.06 | 144.04 | – | – |
Ribavirin | 486.4 | 11.6 | 41.93 | 11.3 | 24.69 | 29.7 | 16.38 |