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Table 7 Standard addition technique data for FPV, CEF and MFX using the described models

From: Green chemometric-assisted UV-spectrophotometric methods for the determination of favipiravir, cefixime and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in pharmaceutical form and spiked human plasma

Pharmaceutical

PLS

GA-PLS

Drug Conc (μg/mL)

PLS found (μg/mL)

GA-PLS found (μg/mL)

FPV

CEF

MFX

FPV

CEF

MFX

Pure added (μg/mL)

% R*

Pure added (μg/mL)

% R*

Pure added (μg/mL)

% R*

Pure added (μg/mL)

% R*

Pure added (μg/mL)

% R*

Pure added (μg/mL)

% R*

FPV (3)

(3.04)*

(3.02)*

3

97.67

3

100.33

3

99.33

3

101.33

3

99.33

3

98.67

CEF (3)

(3.07)*

(2.95)*

3.5

101.71

3.5

98.86

3.5

102.29

3.5

99.14

3.5

98.29

3.5

101.14

MFX (3)

(2.95)*

(3.03)*

4

98.75

4

101.75

4

101.50

4

100.75

4

99.25

4

99.50

Mean

 

99.38

 

100.31

 

101.04

 

100.41

 

98.96

 

99.77

%RSD

 

2.109

 

1.442

 

1.513

 

1.130

 

0.588

 

1.263

  1. *Average of three determinations
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BMC Chemistry

ISSN: 2661-801X

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