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Table 3 Determination of the antimicrobial activity of compounds (4d, 5a, 5b, and 7b) against different antibacterial and fungal strains

From: Novel synthesis of new triazine sulfonamides with antitumor, anti-microbial and anti-SARS-CoV-2 activities

Microorganism

Sample

Standard antibiotic

4d

5a

5b

7b

Gram negative bacteria

 

Gentamicin

Escherichia coli

(ATCC:10536)

NT

NA

NA

NA

27 ± 1.0

Klebsiella pneumonia

(ATCC:10031)

NT

NA

NA

NA

25 ± 1.0

Pseudomonas aeruginosa

(ATCC:27853)

NT

NA

NT

11.3 ± 0.6

27.3 ± 0.6

Gram positive bacteria

 

Ampicillin

Staphylococcus aureus

(ATCC:13565)

9.3 ± 

0.6

11.6 ± 

0.6

9.6 ± 0.6

NA

21.7 ± 0.6

Streptococcus mutans

(ATCC:25175)

NA

NA

10.3 ± 0.6

NA

30 ± 1.0

Fungi

 

Nystatin

Candida albicans

(ATCC:10231)

NA

9.6 ± 

0.6

NA

NA

21 ± 1.0