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Table 2 Determination of the antimicrobial activity of compounds (3a, 3b, 3c, 4a, 4b and 4c) against different antibacterial and fungal strains

From: Novel synthesis of new triazine sulfonamides with antitumor, anti-microbial and anti-SARS-CoV-2 activities

Microorganism

Sample

Standard antibiotic

3a

3b

3c

4a

4b

4c

Gram negative bacteria

 

Gentamicin

Escherichia coli

(ATCC:10536)

NA*

NA

NA

11.6 ± 

0.6

NT

NA

27 ± 1.0

Klebsiella pneumonia

(ATCC:10031)

NA

NT**

NA

NT

NT

NA

25 ± 1.0

Pseudomonas aeruginosa

(ATCC:27853)

NA

NT

NA

NT

NT

NA

27.3 ± 0.6

Gram positive bacteria

 

Ampicillin

Staphylococcus aureus

(ATCC:13565)

NA

NA

NA

11.3 ± 

0.6

NA

NA

21.7 ± 0.6

Streptococcus mutans

(ATCC:25175)

NA

NA

NA

NA

NA

NA

30 ± 1.0

Fungi

 

Nystatin

Candida albicans

(ATCC:10231)

12.3 ± 

0.6

NA

13.3 ± 0.6

NA

NA

NA

21 ± 1.0

  1. *NA: No activity; **NT: Not tested