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Table 2 Regression coefficients, R2, adjusted R2 and probability values for the final reduced models

From: Enhancing the efficacy of nano-curcumin on cancer cells through mixture design optimization of three emulsifiers

Regression coefficient

Particle size

(Y1, nm)

Zeta-potential

(Y2, mV)

a1

23

−4.98

a2

255

−11.55

a3

165

−18.62

a12

749

−28.57

a13

3171

13.69

a23

1178

22.17

a123

−16,234

−48.14

R2 (%)

96.4

93.8

R2adj (%)

91.01

81.41

F-value

44.42

0.91

Lack-of-Fit (p-value)

0.82

0.77