Table 1 Central composite design and response variables for production of Curcumin nanodispersions
Run | Tween 80 (X1, g) | Arabic Gum (X2, g) | PEG (X3, g) | Particle size (Y1, nm) | Zeta-potential (Y2, mV) |
|---|---|---|---|---|---|
1 | 0.75 | 0.00 | 0.75 | 72.5 | −24.70 |
2 | 0.00 | 0.00 | 1.50 | 172.0 | −27.90 |
3 | 0.00 | 0.75 | 0.75 | 496.0 | −10.02 |
4 | 0.25 | 0.25 | 1.00 | 355.0 | −18.78 |
5 | 0.50 | 0.50 | 0.50 | 107.0 | −24.30 |
6 | 1.50 | 0.00 | 0.00 | 16.5 | −7.50 |
7 | 0.25 | 1.00 | 0.25 | 266.0 | −21.60 |
8 | 0.00 | 1.50 | 0.00 | 239.7 | −17.22 |
9 | 0.75 | 0.75 | 0.00 | 304.0 | −28.40 |
10 | 0.50 | 0.50 | 0.50 | 89.5 | −17.50 |
11 | 1.00 | 0.25 | 0.25 | 289.7 | −28.50 |
12 | 0.5 | 0.5 | 0.5 | 96.0 | −23.20 |