Table 1 Infrared absorption bands and different modes of vibration for BIS and its active metabolite
Studied Drug | Groups | Peak assignment | Expected and/or reported values peak (cm− 1) | Present method values peak (cm− 1) |
|---|---|---|---|---|
Biscodyl | C-O of the ester group | C-O | 1250–1310 | 1301 |
The tertiary amine of the pyridine ring | C = N | 1640–1690 | 1640 | |
Carbonyl | C = O stretching | 1690–1760 | 1755 | |
Active Metabolite | Aromatic alcohol | O-H | 3200–3650 | 3309 |
The tertiary amine of the pyridine ring | C = N | 1640–1690 | 1640 | |
Alcohol | C-OH | 1110–1337 | 1273 |