Table 4 EC50 values of some compounds with better inhibitory activity against Xoo, Xoc
From: Sulfonate derivatives bearing an amide unit: design, synthesis and biological activity studies
Compd. | Xoo | Xoc | ||||||
|---|---|---|---|---|---|---|---|---|
Regression eq. | R2 | EC50(µg/mL)a | Regression eq. | R2 | EC50(µg/mL)a | |||
A4 | y = 1.83x + 2.44 | 0.96 | 24.87 ± 1.22 | y = 2.15x + 1.81 | 0.95 | 30.12 ± 1.03 | ||
A15 | - | - | - | y = 4.19x-1.69 | 0.99 | 39.59 ± 1.44 | ||
A16 | - | - | - | y = 2.16x + 2.25 | 0.95 | 18.75 ± 1.16 | ||
B7 | y = 1.27x + 2.69 | 0.96 | 66.88 ± 2.23 | y = 2.42x + 0.57 | 0.97 | 67.90 ± 1.90 | ||
C4 | y = 1.58x + 2.66 | 0.97 | 30.04 ± 2.01 | y = 3.15x-0.17 | 0.99 | 43.85 ± 2.28 | ||
C7 | - | - | - | y = 3.90x-1.78 | 0.99 | 54.56 ± 1.58 | ||
BT | y = 2.21x + 1.91 | 0.99 | 25.12 ± 1.03 | y = 1.39x + 2.38 | 0.98 | 76.38 ± 3.23 | ||
TC | y = 1.41x + 2.66 | 0.99 | 45.81 ± 1.72 | y = 1.50x + 1.82 | 0.94 | 130.49 ± 2.50 | ||