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Table 1 Intestinal Alkaline phosphatase inhibitory activity of 7a-7f derivatives

From: Exploration of newly synthesized azo-thiohydantoins as the potential alkaline phosphatase inhibitors via advanced biochemical characterization and molecular modeling approaches

Compound

Alkaline phosphatase IC50 ± SEM (µM)

Compound

Alkaline phosphatase IC50 ± SEM (µM)

7a

4.847 ± 0.985

7d

3.149 ± 0.853

7b

1.276 ± 0.214

7e

0.308 ± 0.065

7c

3.071 ± 0.687

7f

0.836 ± 0.097

L–Phenyl alanine

80.2 ± 1.1

  1. Values are presented as Mean ± SEM (Standard error of the mean)
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BMC Chemistry

ISSN: 2661-801X

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