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Table 3 Assay results for the determination of FVM, and IVM in synthetic mixtures

From: Utility of sustainable ratio derivative spectrophotometry for the concurrent assay of synergistic repurposed drugs for COVID-19 infections; Insilico pharmacokinetics proof

% Recoverya

Analyte

FVM

IVM

Method

FFZD

FFR

DWZ

FFZD

FFR

DWZ

Mix 1b

100.42

100.79

99.89

100.42

100.79

99.89

Mix 2c

99.68

100.28

99.98

98.73

98.83

98.16

Mix 3d

99.47

100.62

100.20

99.47

100.62

100.20

Mean ± 

99.86 ± 

100.56 ± 

100.02 ± 

99.54 ± 

100.08 ± 

99.41 ± 

SD

0.50

0.26

0.16

0.85

1.09

1.10

  1. aThe average of the three determinations
  2. bMix 1 containing 20 FVM and 2.5 IVM μg/mL
  3. cMix 2 containing 10 FVM and 10 IVM μg/mL
  4. dMix 3 containing 5 FVM and 15 IVM μg/mL
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BMC Chemistry

ISSN: 2661-801X

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