Table 3 Stability results of abexinostat in plasma under different conditions (n = 5)
Analyte | Concentration (ng/mL) | Room temperature, 3 h | Autosampler 10 ℃, 4 h | Three freeze–thaw | − 80 ℃, 3 weeks | ||||
|---|---|---|---|---|---|---|---|---|---|
RSD (%) | RE (%) | RSD (%) | RE (%) | RSD (%) | RE (%) | RSD (%) | RE (%) | ||
Abexinostat | 5.00 | 4.6 | − 5.1 | 10.6 | − 1.7 | 7.9 | − 7.3 | 6.3 | 5.4 |
40 | 3.4 | 2.2 | 5.5 | 15.0 | 2.2 | − 10.3 | 6.9 | 3.3 | |
80 | 3.7 | 0.2 | 3.1 | − 11.9 | 2.5 | 13.8 | 4.1 | − 1.6 | |