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Table 2 Recovery and matrix effect of abexinostat in rat plasma (n = 6)

From: Development of an UPLC-MS/MS method for quantitative analysis of abexinostat levels in rat plasma and application of pharmacokinetics

Analyte

Concentration (ng/mL)

Recovery (%)

Matrix effect (%)

  

Mean ± SD

RSD (%)

Mean ± SD

RSD (%)

 

5.00

81.3 ± 11.3

13.8

111.5 ± 13.6

11.4

Abexinostat

40

96.1 ± 2.0

2.1

110.2 ± 2.9

2.6

 

80

99.6 ± 3.3

3.3

111.8 ± 4.3

4.5