Fig. 3
From: Computational design of anti-cancer peptides tailored to target specific tumor markers
Post-Docking Interaction of CXCR1 with Respective Peptides. Left Panel: Schematic Representation using LIGPLOT. Pink lines represent non-ligand bonds. Cyan lines denote ligand bonds. Green dotted lines, with annotated distances, indicate hydrogen bonds. Red hemispheres signify hydrophobic interactions. Right Panel: Visualization in Chimera. All hydrophobic residues are depicted in green. The ligands are consistently represented in pink in all interactions. C9: His334 (red), Arg135 (cyan), Ala138 (yellow), and Arg242 (purple) form hydrogen bonds. C7: His334 (red), Arg333 (yellow), and Arg242 (purple) form hydrogen bonds. C5: Arg135 (red), Arg242 (yellow), Ser343 (purple), and Asn345 (cyan) form hydrogen bonds. C1: Ser72 (red), Val73 (purple), Asp75 (yellow), Arg242 (cyan), Arg333 (light green) and His334 (blue) form hydrogen bonds. C26: Ser72 (red) and Val73 (yellow) form a hydrogen bond