Table 4 Advantages and outcomes of the proposed spectrophotometric methods
Method | Advantages & outcomes | Limitations |
|---|---|---|
DW | • Can determine the co-administered ASP &ROX successfully in different matrices • Applied on zero order spectra, consequently less noise is obtained • No need for further manipulation so, it does not require special software • Has the least mathematical slope & intercept of linear equation, so low interference and error index are assured • Has RSD% less than 2 which offers accurate and precise determinations | • Applied on Zero order spectra, so some minor features of the spectra may be neglected • The wavelength pairs of choice may be critical which propose meticulous analysis |
RD | • Can determine the co-administered ASP &ROX successfully in different matrices • Applied on ratio spectra, that keeps the potential interference constant throughout the whole spectrum • Allow wide choice of wavelength pairs for determination • Critical determinations are avoided • Has low mathematical slope & intercept of linear equation, so low interference and error index are obtained • Has RSD% less than 2 which offers accurate and precise determinations | • Ratio spectra may enhance base line noise • It needs one more manipulation step • It requires divisor selection optimization |
1DD | • Can determine the co-administered ASP &ROX successfully in different matrices • Applied on ratio spectra, that keeps the potential interference constant throughout the whole spectrum • Derivatization cancels the interfering contribution throughout the spectra • Derivative manipulation may enhance some minor features that permit clear determination • Allow variable wavelengths for quantitation • Has low mathematical slope & intercept of linear equation, so low interference and error index are obtained • Creates new sensitive analytical signals giving the chance of more sensitive results • Has RSD% less than 2 which offers accurate and precise determinations | • Ratio spectra with derivative steps may enhance base line noise • It needs more manipulation steps • It requires divisor and derivatization parameters optimization |