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Table 6 CDK2 inhibitory activity of compound 7e

From: Novel tetrahydroisoquinolines as DHFR and CDK2 inhibitors: synthesis, characterization, anticancer activity and antioxidant properties

Compd. no.

M.W. (g/mol)

CDK2 inhibition (IC50 ± SD; µM)

7e

578

0.149 ± 0.007

Roscovitine

354.5

0.380 ± 0.008

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BMC Chemistry

ISSN: 2661-801X

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