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Table 2 Cytotoxicity (IC50) of compounds 7e and 8d and Doxorubicin against normal cell line WI-38 cell line

From: Novel tetrahydroisoquinolines as DHFR and CDK2 inhibitors: synthesis, characterization, anticancer activity and antioxidant properties

Code

Toxicity on WI38 IC50 µM ± SD

Selectivity index (SI)

7e

19.734 ± 0.79

127.29

8d

23.301 ± 0.93

45.24

Doxorubicin

11.433 ± 0.37

52.4

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BMC Chemistry

ISSN: 2661-801X

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