Table 1 Cytotoxicity (IC₅₀) of compounds 1, 3–6, 7a–7e, 8a–e and doxorubicin as a standard against both MCF7, A549 cell lines

1.857 ± 0.008

2.219 ± 0.002

0.562 ± 0.007

2.469 ± 0.006

3.074 ± 0.008

0.918 ± 0.002

0.924 ± 0.007

1.247 ± 0.002

0.329 ± 0.005

3.736 ± 0.002

2.218 ± 0.004

1.586 ± 0.001

0.474 ± 0.006

0.987 ± 0.002

1.491 ± 0.004

0.496 ± 0.003

0.495 ± 0.002

0.446 ± 0.004

0.211 ± 0.002

0.155 ± 0.003

0.872 ± 0.003

1.045 ± 0.006

3.800 ± 0.008

0.527 ± 0.002

0.215 ± 0.005

0.332 ± 0.002

0.117 ± 0.004

0.515 ± 0.002

0.461 ± 0.002

1.329 ± 0.004

0.053 ± 0.002

0.218 ± 0.005