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Table 5 Application of the proposed spectroscopic methods for the determination of ALC in Orchinohist® eye drops

From: Determination of antihistaminic drugs alcaftadine and olopatadine hydrochloride via ion-pairing with eosin Y as a spectrofluorimetric and spectrophotometric probe: application to dosage forms

Parameters

Reported method [8]

Method A

Method B

% Recoverya

100.20

101.05

99.98

Standard deviation, SD

0.55

1.19

0.91

Number of determinations

5

5

5

t-valuea

 

1.46

0.81

F-value a

 

4.72

0.36

  1. aTabulated value at 95% confidence limit; t = 2.306 and F = 6.338