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Table 1 Distribution of the test set active inhibitors and inactive decoys for the target kinases VEGFR-2, FGFR-1, and BRAF

From: Receptor-based pharmacophore modeling, molecular docking, synthesis and biological evaluation of novel VEGFR-2, FGFR-1, and BRAF multi-kinase inhibitors

Target kinase

Total test set compounds

Active inhibitors

Inactive decoys

VEGFR-2

827

26

801

FGFR-1

620

20

600

BRAF

940

27

913

Total

2387

73

2314