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Table 6 Assay of CFX and PLN in their single commercial eye drops by the suggested first derivative synchronous method

From: Eco-friendly, sensitive and inventive first derivative synchronous spectrofluorimetric determination of ciprofloxacin and phenylephrine in their pure form, single and combined eye drops

Parameter

Conc taken (µg /mL)

% Found a

Comparison method [36] % Found a

Ciprocin® eye drops (0.3% CFX)

0.5

100.16

100.21

1.0

99.35

99.69

2.0

98.95

101.95

3.0

102.09

98.90

Mean ± SD

100.14 ± 1.39

100.19 ± 1.29

t

0.04

 

F

1.17

Phenylmedrin® eye drops (2.5% PLN)

0.02

98.35

101.43

0.05

99.53

102.14

0.07

100.16

100.48

0.1

101.89

99.64

Mean ± SD

99.98 ± 1.48

100.92 ± 1.09

t

1.03*

 

F

1.82*

  1. a The average of three separate results
  2. * The tabulated t and F values are 2.45 and 9.28 respectively at p = 0.05 [39]