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Table 3 Minimum inhibitory concentration (MIC; µg) and minimum bactericidal concentration (MBC; µg) for six antibacterial agents on three strains of Staphylococcus aureus

From: Vancomycin and nisin-modified magnetic Fe3O4@SiO2 nanostructures coated with chitosan to enhance antibacterial efficiency against methicillin resistant Staphylococcus aureus (MRSA) infection in a murine superficial wound model

S. aureus species

Antibacterial agents (μg/mL)

 

Fe3O4@SiO2

Fe3O4@SiO2@CS

Nisin

Fe3O4@SiO2@CS

NISIN-

Vancomycin

Fe3O4@SiO2@CS-VANCO

 

MIC

MBC

MIC

MBC

MIC

MBC

MIC

MBC

MIC

MBC

MIC

MBC

MRSA

250

500

125

250

18

18

52

52

1.84

1.84

0.92

0.92

MSSA

250

250

125

125

12

12

48

48

1.46

1.46

0.73

0.73

ARSA

250

250

125

125

12

18

48

52

1.62

1.62

0.81

0.81

  1. S. aureus Staphylococcus aureus, MRSA and MSSA methicillin-resistant and -susceptible S. aureus, ARSA ampicillin-resistant S. aureus, MIC minimum inhibitory concentration, MBC minimum bactericidal concentration, CS chitosan, VANCO vancomycin