The effectiveness of multivariate and univariate spectrophotometric techniques for the concurrent estimation of ornidazole and ciprofloxacin HCl in tablet formulation and spiked serum: estimating greenness and whiteness profile

Table 9 Statistical comparison between the elaborated UV tools and the reference HPLC tool for CI and OR estimation in tablet forms

Tablet formulation	CI			OR			HPLC^a
Tablet formulation	ANN	FSD	MC	ANN	FSD	MC	CI	OR
Average^b	100.16	100.57	100.07	100.86	100.53	99.82	100.45	100.28
SD	1.82	0.86	1.59	1.70	1.08	1.49	0.94	1.45
Variance	3.3282	0.7378	2.5243	2.8826	1.1607	2.2267	0.8884	2.1019
t-value^c	0.3169	0.2034	0.4604	0.5862	0.3082	0.4935	–	–
f-value^c	3.7464	1.2041	2.8415	1.3715	1.8109	1.0594	–	–

^aC-18 column utilizing acetonitrile: water as the mobile phase with (45:55v/v) ratio, pH sets to 3.0 via O-phosphoric acid, flow rate 1 ml/min, estimation at 299 nm
^bn = 5
^cf(0.05)6.388, t(0.05)2.306

ISSN: 2661-801X