Table 5 Statistical comparison of the results obtained by the proposed TLC-densitometry method and the reported HPLC method for the analysis of Capozide ® tablet

Captopril

 Mean (%)^a

101.96

102.08

 SD

0.34

0.37

 N

6

6

 Student’s t test (2.228)^c

0.59

–

 F test (5.505)^c

1.18

–

Standard addition technique

1.20

100.79

1.50

100.85

2.00

100.55

 Mean ± SD

100.73 ± 0.16

Hydrochlorothiazide

 Mean (%)^a

101.55

101.30

 SD

0.40

0.30

 N

6

6

 Student’s t test (2.228)^c

1.26

–

 F test (5.505)^c

1.78

–

Standard addition technique

0.50

100.29

0.70

100.35

1.00

100.56

 Mean ± SD

100.40 ± 0.14