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Table 7 Statistical comparison between the developed method and the reported one using pure samples of the studied drugs

From: Chromatographic analysis of triple cough therapy; bromhexine, guaiafenesin and salbutamol and pharmaceutical impurity: in-silico toxicity profile of drug impurity

Parameters

GUF

BR

SAL

Reported method [27]

GUF

BR

SAL

TLC

HPLC

TLC

HPLC

TLC

HPLC

Mean

98.59

99.77

99.84

99.83

99.76

99.09

99.17

100.89

98.89

SD

1.49

1.24

0.84

1.27

1.22

1.41

2.29

1.43

1.42

Variance

2.22

1.55

0.72

1.63

1.50

1.98

5.26

1.93

2.02

N

9

9

9

9

9

9

8

8

8

Student's t-test (2.130)

0.63

0.67

2.01

1.72

1.35

0.29

–

–

–

F-test (3.500)

2.37

3.39

2.70

1.19

1.34

1.02

–

–

–

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BMC Chemistry

ISSN: 2661-801X

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