Table 3 Reproducibility and precision data for the analysis of terbutaline sulphate and bambuterol hydrochloride using the proposed 1H-qNMR method
Drug | Conc. | Intra-day | Conc. | Inter-day | ||||
|---|---|---|---|---|---|---|---|---|
% error | % RSD | Mean ± S.D | % error | % RSD | Mean ± S.D | |||
Terbutaline | 2.0 | 0.15 | 0.26 | 101.8 ± 0.27 | 2.0 | 0.64 | 1.12 | 98.73 ± 1.10 |
4.0 | 1.09 | 1.89 | 100.07 ± 1.89 | 4.0 | 0.34 | 0.59 | 98.33 ± 0.58 | |
6.0 | 0.10 | 0.18 | 98.1 ± 0.17 | 12.0 | 0.97 | 1.68 | 99.93 ± 1.68 | |
Bambuterol | 2.0 | 0.15 | 0.26 | 101.8 ± 0.27 | 2.0 | 1.59 | 2.76 | 99.95 ± 2.76 |
4.0 | 1.02 | 1.76 | 99.25 ± 1.75 | 4.0 | 1.1 | 1.91 | 100.65 ± 1.92 | |
8.0 | 1.12 | 1.95 | 101.03 ± 1.97 | 16.0 | 0.97 | 1.69 | 100.08 ± 1.69 | |