Table 2 Comparative analytical data for the determination of Terbutaline sulphate and Bambuterol hydrochloride in their pure form by proposed 1H-qNMR method and a comparison spectrofluorimetric method
Drug | Proposed method | Comparison method ]10[ | |||
|---|---|---|---|---|---|
Trebutaline mg/ml | Amount taken | Amount found | % Found | Amount taken (µg/ml) | % Found |
1.0 | 1.0 | 102.9 | 0.4 | 101.5 | |
2.0 | 2.0 | 100.28 | 0.8 | 100.63 | |
4.0 | 3.92 | 98.04 | 1.6 | 99.06 | |
12.0 | 12.0 | 100.87 | 3.2 | 98.84 | |
16.0 | 15.93 | 99.6 | 4.0 | 100.85 | |
Mean | 100.34 | 100.73 | |||
± S.D | 1.8 | ||||
Student´s T-test | 0.17 (2.3)* | ||||
Variance F-test | 2.32 (5.05)* | ||||
Bambuterol mg/ml | 1.0 | 1.01 | 101.76 | 0.2 | 102.0 |
2.0 | 2.05 | 102.67 | 0.4 | 98.75 | |
4.0 | 4.01 | 100.27 | 1.6 | 99.75 | |
8.0 | 7.85 | 98.22 | 4.0 | 100.33 | |
16.0 | 16.06 | 100.38 | 6.0 | 99.83 | |
Mean | 100.66 | 99.97 | |||
± S.D | 1.69 | ||||
Student´s T-test | 0.57 (2.3)⁎ | ||||
Variance F-test | 2.01 (5.05)⁎ | ||||