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Table 11 Penalty points for greenness assessment of the proposed methods by Eco scale tool

From: Development of chromatographic methods to determine multivitamins formulation depending on their solubility and polarity: comparative study using three greenness assessment tools

Hazard

Penalty points (Method A)

Penalty points (Method B)

Ammonium acetate buffer

0

–

Sodium dihydrogen phosphate buffer

–

0

Sodium chloride

–

0

Glacial acetic acid

4

–

Ortho-Phosphoric acid

–

4

Methanol

12

 

Instruments energy

1

1

Occupational hazard

0

0

Waste

6

6

Total penalty points

23

11

Analytical eco-scale total score

77

89

  1. * > 75 represents excellent green analysis, > 50 represents acceptable green analysis, < 50 represents inadequate green analysis