Table 2 Response optimization of 23 factorial design for RP-HPLC–UV separation of DES, RUP, FEX and MKT*
Response | Goal | Lower | Target | Upper | Weight | Importance | Predicted responses | Desirability | Composite desirability |
|---|---|---|---|---|---|---|---|---|---|
Parameters | |||||||||
 MKT | |||||||||
  Tr | Target | 13 | 14.3 | 15 | 1 | 1 | 14.30 | 1 | 0.779 |
  Rs | Target | 3 | 3.45 | 4.5 | 1 | 1 | 3.45 | 1 | |
  Tf | Target | 0.9 | 1.11 | 1.3 | 1 | 1 | 1.21 | 0.474 | |
 FEX | |||||||||
  Tr | Target | 10 | 11.3 | 12 | 1 | 1 | 11.30 | 1 | 1.00 |
  Rs | Target | 0.9 | 0.93 | 1.2 | 1 | 1 | 0.93 | 1 | |
  Tf | Target | 3 | 3.07 | 4 | 1 | 1 | 3.07 | 1 | |
 DES | |||||||||
  Tr | Target | 7 | 8 | 9 | 1 | 1 | 8 | 1 | 1.00 |
  Rs | Target | 2.6 | 3.75 | 4.5 | 1 | 1 | 3.75 | 1 | |
  Tf | Target | 1.4 | 1.4 | 1.68 | 1 | 1 | 1.42 | 1 | |
 RUP | |||||||||
  Tr | Target | 8 | 9.72 | 10 | 1 | 1 | 9.72 | 1 | 1.00 |
  Rs | Target | 3 | 3.21 | 4.5 | 1 | 1 | 3.21 | 1 | |
  Tf | Target | 0.9 | 1.11 | 1.5 | 1 | 1 | 1.11 | 1 | |