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Table 3 CC50 value of compound 13 against normal VERO cells and its selectivity index

From: Synthesis, antileishmanial, antimalarial evaluation and molecular docking study of some hydrazine-coupled pyrazole derivatives

Test compounds

Structure

CC50 (µM)

IC50 (µM)

SI

13

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117.79

0.60442

194.88

Miltefosine

–

99.7

7.897

12.63

  1. CC50 is the concentration at which 50% of the VERO cells survive and IC50 of antileishmanial activity. SI is the selectivity index, SI = CC50/IC50
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BMC Chemistry

ISSN: 2661-801X

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