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Table 2 The extraction recovery rate and matrix effect (n = 5)

From: Simultaneous determination of colistin sulfate and tigecycline in human plasma by liquid chromatography-tandem mass spectrometry method

Analyte

Quality control concentration

(µg/mL)

Extraction recovery rate

(%)

RSD

(%)

Matrix effect

(%)

RSD

(%)

Colistin sulfate

0.1

87.75 ± 7.74

8.82

99.40 ± 6.96

7.01

1

88.61 ± 4.50

5.07

101.24 ± 2.64

2.60

8

91.22 ± 2.62

2.88

102.53 ± 1.60

1.56

Tigecycline

0.05

88.89 ± 2.38

2.68

102.20 ± 5.37

5.25

0.5

90.76 ± 4.56

5.02

102.77 ± 11.46

11.16

4

90.05 ± 4.65

5.17

105.26 ± 2.37

2.25