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Table 4 Estimated exposures (ng/person/day) to coumarin from Swedish and US STPs

From: Analysis of coumarin and angelica lactones in smokeless tobacco products

STP

Coumarin concentration by brand (ng/g)

STP consumption (g/day)

Extraction in mouth (%)

Exposure (ng/day) (using highest reported consumption rate)

Min

Max

Min

Max

Swedish P snus

< 30

486

14.4b, 11–12c

24

< 104

2288

Swedish L snus

< 30

331

20.8b, 29–32c

24

< 230

2542

US MSa

206

1033

7.3d, 10e, 12.4f, 5.3g, 20.4h

24

613a

5057a

US DS

< 30

3347

N/A

24

N/A

N/A

US CT

< 30

247

N/A

24

N/A

N/A

  1. N/A not available
  2. a Actual exposures may be lower due to expectoration
  3. b Andersson et al. [60]
  4. c Digard et al. [61]
  5. d Maxwell [62]
  6. e Surgeon General [63]
  7. f Hatsukami et al. [64]
  8. g Hecht et al. [67]
  9. h Hecht et al. [65]
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BMC Chemistry

ISSN: 2661-801X

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