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Table 5 Suzuki coupling of p-bromoacetophenone (5) with arylboronic acids using the catalyst 4 under thermal heating and microwave irradiation conditions

From: Novel pyridine-based Pd(II)-complex for efficient Suzuki coupling of aryl halides under microwaves irradiation in water

Entry

R

Conversion

∆ yield %

MW yield %

1

4-CH3

100

90

97

2

4-CI

100

93

94

3

4-F

100

82

90

4

3-NH2

100

76

96

5

2,4,6-(CH3)3

100

83

90

  1. Conditions: Bromide: 1 mmol; arylboronic acid: 1.2 mmol; TBAB: 0.6 mmol; KOH: 2 mmol; water: 5 mL, Pd-complex: 4: 0.25 mol%, microwave heating (400 W) at 160 °C and thermal heating at 100 °C
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BMC Chemistry

ISSN: 2661-801X

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