Entry | X | R | Yield %a,b
|
---|
1 | CI | H | 100 (90) |
2 | CI | 4-OH | 90 (82) |
3 | CI | 3-NH2
| 85 (74) |
4 | Br | H | 100 (78) |
5 | | | H | 100 (82) |
-
aConditions: haloaromatic/ boronic acid/ KOH/ TBAB /water (5 mL): 1/1.2/2/0.6, at 100 °C for 1 h
-
bConversions were based on 1H NMR of the crude product and the values between parentheses refer to the isolated yields