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Table 3 Response of various microorganisms to some synthesized compounds in vitro (culture)

From: Regioselectivity of 1,3-dipolar cycloadditions and antimicrobial activity of isoxazoline, pyrrolo[3,4-d]isoxazole-4,6-diones, pyrazolo[3,4-d]pyridazines and pyrazolo[1,5-a]pyrimidines

Microorganism/compound no.

Staphylococcus albus (G+)

Streptococcus faecalis (G+)

Bacillus subtilis (G+)

Echerichia coli (G−)

Aspergills flvus (fungus)

Candida albicans (fungus)

Ampicillin/tetracycline

34R/27

37/31

33/30

39/34

0.0/0.0

20/37

3

16

13

18

18

0.0

16

5

19

16

12

17

0.0

13

8a

16

15

12

17

0.0

14

8b

15

16

14

16

0.0

14

8c

17

15

12

17

0.0

13

12a

15

14

13

16

0.0

13

12b

14

16

13

13

0.0

14

22a

16

15

14

15

0.0

14

22b

15

18

12

15

0.0

14

22c

16

15

14

16

0.0

14

  1. St. reference standard; ampicillin and tetracycline were used as a slandered antibacterial agent and antifungal agent. Values show zone of inhibition in mm. Diameter of the inhibition zones were: high (11–15 mm), moderate (6–10 mm), slight (1–5 mm) and negative (0)
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BMC Chemistry

ISSN: 2661-801X

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