Synthesis and antibacterial and antifungal activities of N-(tetra-O-acetyl-β-d-glucopyranosyl)thiosemicarbazones of substituted 4-formylsydnones

Table 2 Synthesis of 3-aryl- and 3-cyclohexyl-4-formylsydnone N-(tetra-O-acetyl-β-d-glucopyranosyl)thiosemicarbazones (4a–o) under conventional and μ-wave heating

Entry	R	Reaction time (min)		Yield (%)
Entry	R	Conventional heating	MW heating	Conventional heating	MW heating
4a	H	100	25	50	71
4b	2-Me	120	28	55	75
4c	3-Me	130	30	55	73
4d	4-Me	130	30	56	76
4e	2,3-diMe	130	35	55	70
4f	2,4-diMe	130	35	50	68
4g	4-Et	120	28	60	83
4h	3-OMe	130	30	60	78
4i	4-OMe	130	30	60	81
4j	4-OEt	130	25	60	82
4k	4-F	130	30	55	65
4l	4-Br	150	35	55	63
4m	4-I	130	35	57	68
4n	2-Me-5-Cl	140	45	50	43
4o	Cyclohexyl^a	130	30	60	85

ISSN: 2661-801X