From: Using water–solvent systems to estimate in vivo blood–tissue partition coefficients
Process | p | R2 | c0 | c1 |
---|---|---|---|---|
Blood–brain | 0.003 | 0.92 | 0.529 | 0.173 |
Blood–muscle | 0.3 | 0.29 | 0.080 | 0.021 |
Blood–liver | 0.3 | 0.30 | 0.287 | 0.044 |
Blood–lung | 0.07 | 0.60 | 0.256 | 0.124 |
Blood–kidney | 0.3 | 0.26 | 0.489 | 0.050 |
Blood–heart | 0.08 | 0.59 | 0.124 | 0.080 |
Blood–skin | 0.04 | 0.71 | −0.117 | 0.120 |
Blood–fat | 0.0005 | 0.96 | 0.046 | 0.297 |
Water–skin | 0.02 | 0.76 | 0.491 | 0.311 |
Skin-permeation | 0.01 | 0.84 | −5.465 | 0.439 |