Fig. 12From: Structural and spectral investigations of the recently synthesized chalcone (E)-3-mesityl-1-(naphthalen-2-yl) prop-2-en-1-one, a potential chemotherapeutic agent a The title compound 3 was fit well in the cavity of histone acetyltransferase enzyme. b Docking conformation of title compound 3 (generated by MOE docking software) properly accommodated into the binding cavity of histone acetyltransferase enzyme and developed hydrogen bond and two arene-cation and arene-arene interactions with active site residue Arg176, Arg124 and Trp180. histone acetyltransferaseBack to article page