From: Organocatalysis in heterocyclic synthesis: DABCO as a mild and efficient catalytic system for the synthesis of a novel class of quinazoline, thiazolo [3,2-a]quinazoline and thiazolo[2,3-b] quinazoline derivatives
Entry a
Base
Solvent
Time(min)
Yield (%)
1
DABCO
EtOH
5
81
2
piperidine
30
67
3
morpholine
25
61
4
DBU
15
55
L-proline
40
69
6
K2CO3
60
none
7
CH3CN
35
8
DMF
46
9
Dioxane
51
10
MeOH
68