Micellar liquid chromatographic method for the simultaneous determination of Levofloxacin and Ambroxol in combined tablets: Application to biological fluids

Table 7 Assay results for the determination of LEV and AMB in their prepared tablets

Preparation	Amount taken		Amount found		% Found		Comparison method (35)
	(μg/mL)		(μg/mL)		% Found		Comparison method (35)
	LEV	AMB	LEV	AMB	LEV	AMB	LEV	AMB
Prepared tablet (250 mg LEV+60 mg AMB)	5.0	6.0	25.1500	6.0020	100.60	100.04	100.10	100.68
	20.0	1.2	4.9200	1.2010	98.40	100.12	99.02	103.35
	25.0	4.8	19.7780	4.8250	98.89	102.00	98.16	101.60
$\bar{X}$					100.20*	100.72	99.09	101.88
± SD					±1.64	±1.11	±0.97	±1.36
% RSD					1.63	1.10	0.98	1.33
% Error					0.94	0.64	0.57	0.77
t					0.233	1.143
F					1.418	1.495

N.B. Each result is the average of three separate determinations.
The values of tabulated t and F tests are 2.78 and 19.00 respectively at p = 0.05 [38].
Average LEV concentration found in tablet 250.50 mg and average AMB found 60.14 mg per tablet.

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