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Table 2 Application of the proposed and comparison methods to the determination of the studied drugs in pure forms

From: Spectrophotometric determination of certain CNS stimulants in dosage forms and spiked human urine via derivatization with 2,4-Dinitrofluorobenzene

Parameter

proposed method

Comparison

method(35)

 

Conc.taken

(μg/mL)

Conc.found

(μg/mL)

% Founda

% Founda

PPA

2.0

1.96

98.00

 
 

4.0

4.01

100.25

99.53

 

6.0

5.97

99.50

102.01

 

10.0

10.07

100.70

100.11

 

12.0

12.13

101.08

 
 

18.0

17.81

98.94

 
 

20.0

20.07

100.35

 

x ̄ ± S.D.

99.83 ± 1.08

100.55± 1.29

t

0.339 (2.306)

 

F

1.426 (5.14)

 

Parameter

proposed method

Comparison

Method (36)

 

Conc.

taken

(μg/mL)

Conc.

found (μg/mL)

% Found a

% Found a

EPH

1.0

1.02

102.00

 
 

3.0

2.98

99.33

 
 

5.0

5.02

100.40

102.00

 

7.0

6.94

99.14

99.98

 

8.0

7.98

99.75

101.05

 

9.0

9.10

101.11

 
 

10.0

9.98

99.80

 
 

14.0

13.99

99.93

 

x ̄ ± S.D.

100.18 ± 0.96

100.01 ± 1.01

t

1.264 (2.262)

 

F

1.106 (4.74)

 

Parameter

proposed method

Comparison

Method (37)

 

Conc.

taken

(μg/mL)

Conc.

found

(μg/mL)

% Found a

% Found a

PSE

1.0

1.01

101.00

102.00

 

3.0

3.00

100.00

98.33

 

4.0

3.94

98.50

98.01

 

10.0

10.06

100.60

 
 

12.0

12.10

100.83

 
 

14.0

13.89

99.21

 

x ̄ ± S.D.

100.02 ± 0.99

99.45 ± 2.22

t

0.597 (2.365)

 

F

5.028 (5.79)

 
  1. a Each result is the average of three separate determinations.
  2. *Values between parentheses are the tabulated t and F values, at p 0.05(38).