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Table 3 Validation of the proposed method for the determination of sertraline in pure form and tablets

From: Spectrofluorimetric determination of sertraline in dosage forms and human plasma through derivatization with 9-fluorenylmethyl chloroformate

Concentration added

(μg mL-1)

% Recovery

% RSD

% Error

SER

   

Intra-day

   

0.2

98.75 ± 0.65

0.65

0.33

0.4

100.41 ± 1.07

1.07

0.54

0.6

98.66 ± 0.5

0.5

0.25

Inter-day

   

0.2

99.98 ± 0.82

0.82

0.41

0.4

100.63 ± 0.85

0.85

0.43

0.6

100.74 ± 1.17

1.17

0.59

Lustral Tablets

(50 mg SER/tablet)

   

Intra-day

   

0.2

98.00 ± 1.29

1.29

0.65

0.4

100.41 ± 0.92

0.92

0.46

0.6

100.47 ± 1.35

1.35

0.68

Inter-day

   

0.20

100.19 ± 1.07

1.07

0.54

0.40

99.67 ± 1.56

1.56

0.78

0.60

100.80 ± 0.80

0.80

0.40

  1. Each result is the average of four separate determinations.