Parameter | Amount taken (μg/ml) | Amount found(μg/ml) | %Recovery | Comparison method3 | ||||
---|---|---|---|---|---|---|---|---|
Ebastine in presence of its alkaline degradation product | Â | SFS | FDSFS | SDSFS | SFS | FDSFS | SDSFS | %Recovery |
 | 0.1 | 0.099 | 0.101 | 0.1003 | 99.11 | 100.82 | 100.33 | 100.62 |
 | 0.2 | 0.198 | 0.201 | 0.201 | 99.22 | 100.53 | 100.45 | 99.15 |
 | 0.3 | 0.301 | 0.298 | 0.301 | 100.33 | 99.33 | 100.27 | 99.34 |
 | 0.5 | 0.498 | 0.503 | 0.495 | 99.62 | 100.62 | 99.05 |  |
 | 0.7 | 0.704 | 0.694 | 0.706 | 100.57 | 99.14 | 100.86 |  |
 | 0.8 | 0.806 | 0.793 | 0.795 | 100.75 | 99.13 | 99.38 |  |
 | 1.0 | 0.994 | 1.01 | 0.999 | 99.46 | 100.92 | 99.93 |  |
X¯ ± SD |  |  |  |  | 99.87 ± 0.67 | 100.07 ± 0.83 | 100.04 ± 0.63 | 99.70 ± 0.79 |
Student's t test | Â | Â | Â | Â | 0.96 (1.94) | 0.94 (1.94) | 0.78 (1.94) | Â |
Variance ratio F test | Â | Â | Â | Â | 1.39 (5.14) | 1.1 (5.14) | 1.57 (5.14) | Â |
Ebastine in presence of its acidic degradation product | 0.1 | 0.099 | 0.101 | 0.099 | 99.15 | 100.62 | 99.44 | 100.62 |
 | 0.2 | 0.201 | 0.198 | 0.201 | 100.62 | 99.34 | 100.23 | 99.15 |
 | 0.3 | 0.301 | 0.299 | 0.302 | 100.37 | 99.72 | 100.67 | 99.34 |
 | 0.5 | 0.499 | 0.502 | 0.501 | 99.72 | 100.33 | 100.15 |  |
 | 0.7 | 0.697 | 0.704 | 0.698 | 99.63 | 100.66 | 99.77 |  |
 | 0.8 | 0.807 | 0.796 | 0.799 | 100.84 | 99.46 | 99.81 |  |
 | 1.0 | 0.1003 | 0.1003 | 0.995 | 100.25 | 100.27 | 99.47 |  |
X¯ ± SD |  |  |  |  | 100.08 ± 0.61 | 100.06 ± 0.54 | 99.93 ± 0.44 | 99.70 ± 0.79 |
Student's t test | Â | Â | Â | Â | 0.36 (1.94) | 0.36 (1.94) | 0.39 (1.94) | Â |
Variance ratio F test | Â | Â | Â | Â | 1.68 (5.14) | 2.14 (5.14) | 3.22 (5.14) | Â |
Ebastine in presence of its UV degradation product | 0.1 | 0.1001 | 0.099 | 0.101 | 100.12 | 99.77 | 100.73 | 100.62 |
 | 0.2 | 0.201 | 0.201 | 0.201 | 100.64 | 100.52 | 100.44 | 99.15 |
 | 0.3 | 0.299 | 0.302 | 0.301 | 99.87 | 100.67 | 100.21 | 99.34 |
 | 0.5 | 0.497 | 0.497 | 0.496 | 99.47 | 99.28 | 99.22 |  |
 | 0.7 | 0.694 | 0.698 | 0.695 | 99.19 | 99.73 | 99.34 |  |
 | 0.8 | 0.803 | 0.805 | 0.797 | 100.32 | 100.66 | 99.64 |  |
 | 1.0 | 1.006 | 1.005 | 1.003 | 100.55 | 100.49 | 100.29 |  |
X¯ ± SD |  |  |  |  | 100.02 ± 0.54 | 100.16 ± 0.56 | 99.98 ± 0.58 | 99.70 ± 0.79 |
Student's t test | Â | Â | Â | Â | 0.94 (1.94) | 0.42 (1.94) | 0.44 (1.94) | Â |
Variance ratio F test | Â | Â | Â | Â | 2.14 (5.14) | 1.99 (5.14) | 1.86 (5.14) | Â |