Volume 3 Supplement 1
An online-system for the evaluation of hazardous substances
© Schmidt and Vill; licensee BioMed Central Ltd. 2009
Published: 05 June 2009
More than 50 million compounds with molecular structures are known today. Reliable hazard information is available for only a few thousand of them. Nevertheless, laws and regulations can (and have to) be applied to all chemical substances used in a laboratory. For this purpose, a new web-based system  has been developed for the online evaluation of hazardous substances.
Using a web form which offers a structure editor, any given structure can be submitted to a SciDex-driven backend . In the first step of evaluation, the backend runs a database query to a CLAKS-Database  with more than 140 000 known substances. If the substance is already known to the database, the backend returns the applicable danger symbols, R-and S-Phrases. If it is not found in the database, a substructure analysis according to several regulations will be done. Furthermore, relevant degradation compounds are calculated and analysed.
- Scientific Data Explorer. [http://www.lci-publisher.com/scidex.html]
- Chemikalien-Lager- und Kataster-System. [http://www.chemie.uni-hamburg.de/claks/index.html]
- 67/548/EEC, Amtsblatt der Europäischen Union Nr. 196. 1967, S. 1–98 and Updates
- Chemical Weapons Convention. [http://www.opcw.org/chemical-weapons-convention/]
- Betäubungsmittelgesetz , Bundesgesetzblatt I: 2007, S. 154
- Sprengstoffgesetz , Bundesgesetzblatt I: 2006, S. 2407
This article is published under license to BioMed Central Ltd.