Synthesis, characterization, and antibacterial activity studies of two Co(II) complexes with 2-[(E)-(3-acetyl-4-hydroxyphenyl)diazenyl]-4-(2-hydroxyphenyl)thiophene-3-carboxylic acid as a ligand

Table 4 Antimicrobial activity (MIC and MBC in µg/mL) of synthesized compounds as well as reference antimicrobial drugs

Coumpounds	Inhibition parameters	S. aureus ATCC25923	P. aeruginosa	E. coli ATCC25922	K. pneumoniae 22
7	MIC MBC MBC/CMI	32 > 256 /	128 > 256 /	64 > 256 /	64 > 256 /
11	MIC MBC MBC/CMI	32 > 256 /	64 > 256 /	64 > 256 /	128 > 256 /
12	MIC MBC MBC/CMI	128 > 256 /	32 > 256 /	> 256 > 256 /	64 > 256 /
13	MIC MBC MBC/CMI	64 > 256 /	64 > 256 /	128 > 256 /	64 > 256 /
Reference drugs*	MIC MBC MBC/CMI	8 16 2	8 16 2	16 32 2	16 32 2

/ not determined, MIC Minimum Inhibitory Concentration, MBC Minimum Bactericidal Concentration
^*Ciprofloxacin was tested together with compounds 7, 11, 12 and 13

ISSN: 2661-801X