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Table 2 Enrichment factor for pharmacophore models of each protein with compound 11

From: Hit discovery of potential CDK8 inhibitors and analysis of amino acid mutations for cancer therapy through computer-aided drug discovery

Protein’s name

Enrichment factor

Model-1 (homology model)

6.8

D173A

18.6

D189N

16.9

T196A

8.9

T196D

6.2

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BMC Chemistry

ISSN: 2661-801X

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