Fig. 3From: Hit discovery of potential CDK8 inhibitors and analysis of amino acid mutations for cancer therapy through computer-aided drug discoveryA RMSF of the backbone atoms for Model-1 and CDK8 mutants (D173A, D189N, T196A, and T196D). B Simulated Model-1 and mutated structures after molecular dynamics simulation. The red highlights represent regions numbered 170-200 where mutations occurredBack to article page