Table 9 Determination of FPV, CEF and MFX in spiked human plasma by the proposed models
PLS | GA-PLS | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FPV | CEF | MFX | FPV | CEF | MFX | ||||||||||||
Added (μg/mL) | Found* (μg/mL) | % R | Added (μg/mL) | Found* (μg/mL) | % R | Added (μg/mL) | Found* (μg/mL) | % R | Added (μg/mL) | Found* (μg/mL) | % R | Added (μg/mL) | Found* (μg/mL) | % R | Added (μg/mL) | Found* (μg/mL) | % R |
3 | 2.83 | 94.46 | 3 | 2.91 | 96.84 | 3 | 2.79 | 92.85 | 3 | 2.76 | 92.12 | 3 | 2.79 | 92.91 | 3 | 2.90 | 96.66 |
4 | 3.78 | 94.39 | 4 | 3.73 | 93.34 | 4 | 3.89 | 97.16 | 4 | 3.80 | 95.01 | 4 | 3.82 | 95.49 | 4 | 3.79 | 94.65 |
5 | 4.84 | 96.80 | 5 | 4.75 | 95.09 | 5 | 4.84 | 96.74 | 5 | 4.84 | 96.75 | 5 | 4.72 | 94.46 | 5 | 4.83 | 96.55 |
6 | 5.64 | 93.93 | 6 | 5.89 | 98.10 | 6 | 5.62 | 93.74 | 6 | 5.63 | 93.90 | 6 | 5.83 | 97.18 | 6 | 5.65 | 94.20 |
7 | 6.78 | 96.80 | 7 | 6.80 | 97.08 | 7 | 6.78 | 96.91 | 7 | 6.78 | 96.85 | 7 | 6.78 | 96.86 | 7 | 6.80 | 97.08 |
Mean | 95.28 | Mean | 96.09 | Mean | 95.48 | Mean | 94.93 | Mean | 95.38 | Mean | 95.83 | ||||||
%RSD | 1.476 | %RSD | 1.956 | %RSD | 2.121 | %RSD | 2.104 | %RSD | 1.845 | %RSD | 1.336 | ||||||