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Table 6 The effect of compounds 7b, 15b, 16a and 16c on HepG2 cell lines

From: Synthesis, anticancer evaluation, molecular docking and ADME study of novel pyrido[4ʹ,3ʹ:3,4]pyrazolo[1,5-a]pyrimidines as potential tropomyosin receptor kinase A (TrKA) inhibitors

Code

Apoptosis

Necrosis

Total

Early

Late

7b/HepG2

24.89

5.71

13.72

5.46

15b/HepG2

32.51

2.93

20.12

9.46

16a/HepG2

15.33

8.26

4.32

2.75

16c/HepG2

12.07

6.31

3.20

2.56

cont.HepG2

1.38

0.39

0.15

0.84

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BMC Chemistry

ISSN: 2661-801X

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