Table 1 The IC50 values (the drug concentrations that inhibited 50% of cell proliferation) of the compounds on MCF7 cell line
MCF7 | 20 µg/l | 10 µg/l | 5 µg/l | IC50/µg/l |
|---|---|---|---|---|
Doxo | 98.19 | 89.14 | 75.43 | 2.527 |
1 | 73.65 | 61.39 | 31.71 | 8.153 |
4a | 84.71 | 74.99 | 35.61 | 6.454 |
4b | 70.37 | 55.85 | 22.19 | 9.983 |
7a | 66.12 | 45.66 | 30.13 | 11.17 |
7b | 95.03 | 79.12 | 60.48 | 3.864 |
7c | 92.48 | 69.00 | 40.12 | 6.276 |
7k | 71.12 | 55.16 | 36.19 | 8.418 |
7l | 97.26 | 52.28 | 40.19 | 7.227 |
9a | 75.34 | 49.11 | 36.10 | 8.857 |
9b | 72.13 | 51.19 | 33.82 | 9.161 |
9c | 87.32 | 53.72 | 38.17 | 7.565 |
14a | 77.19 | 48.62 | 25.14 | 9.963 |
15b | 83.62 | 62.92 | 28.52 | 7.893 |
16a | 77.25 | 57.34 | 55.09 | 4.385 |
16b | 80.56 | 55.27 | 54.13 | 4.942 |
16c | 79.61 | 62.79 | 56.81 | 3.805 |