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Table 8 Extraction recoveries of the six drugs in spiked human plasma

From: Therapeutic drug monitoring of six contraindicated/co-administered drugs by simple and green RP-HPLC-PDA; application to spiked human plasma

Drug

concentrations in

plasma (µg/mL)

Extraction recovery (%)± %RSD

IMP

QCL

30.0

99.78 ± 1.60

QCM

40.0

99.99 ± 0.83

QCH

75.0

97.93 ± 1.68

ETP

QCL

50.0

97.22 ± 0.93

QCM

140.0

97.07 ± 0.08

QCH

280.0

98.81 ± 0.48

CLS

QCL

30.0

98.36 ± 1.18

QCM

40.0

97.05 ± 1.41

QCH

75.0

97.68 ± 0.34

MRP

QCL

15.0

98.74 ± 0.60

QCM

35.0

97.21 ± 1.00

QCH

75.0

98.09 ± 0.15

PRB

QCL

15.0

97.26 ± 1.32

QCM

35.0

97.73 ± 1.02

QCH

75.0

99.73 ± 1.02

WRF

QCL

6.0

98.62 ± 0.78

QCM

12.0

99.73 ± 0.93

QCH

25.0

98.38 ± 0.22